Gallery
Structures
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CYP11B2 binding the Cushing's drug osilodrostat
CYP11B2 binding the Cushing's drug osilodrostat
CYP11B2 (purple) binding adrenodoxin (brown) and fadrazole inhibitor (pink sticks)
CYP11B2 binding adrenodoxin and fadrazole inhibitor
17A1 binding steroidal isonitrile
CYP17A1 binding a steroidal isonitrile
Cytochrome P450 17A1 with the prostate cancer drug abiraterone (Zytiga®)
Cytochrome P450 17A1 with the prostate cancer drug abiraterone (Zytiga®).
Human Cytochrome P450 1A1 with alpha-naphthoflavone
Human cytochrome P450 1A1 with alpha-naphthoflavone.
CYP1A1 binding cancer drug erlotinib
CYP1A1 binding cancer drug erlotinib
Human Cytochrome P450 2A13
Human cytochrome P450 2A13.
Human cytochrome P450 2A6
Human cytochrome P450 2A6.
Comparison of cytochrome P450 2A13 and 2A6 active sites
Comparison of cytochrome P450 2A13 and 2A6 active sites.
CYP3A7 (fetal CYP3A) with 4 copies of its DHEAS substrate
CYP3A7 (fetal CYP3A) with 4 copies of its DHEAS substrate
CYP8B1 active site with tioconazole and glycerol (grey sticks)
CYP8B1 active site with tioconazole and glycerol (grey sticks)
Comparison of Human Cytochrome P450 Enzyme Active Sites
Comparison of human cytochrome P450 enzyme active sites.
Cytochrome P450 2A6 I208S/I300F/G301A/S369G mutant with phenacetin
Cytochrome P450 2A6 I208S / I300F / G301A / S369G mutant with phenacetin.
Electron density for flavin mononucleotide in NADPH-cytochrome P450 reductase
Electron density for flavin mononucleotide in NADPH-cytochrome P450 reductase
Histamine dehydrogenase from <i>Nocardioides simplex</i>.
Histamine dehydrogenase from Nocardioides simplex.
Human cytochrome P450 2E1
Human cytochrome P450 2E1 secondary structure.
Human cytochrome P450 2E1 with 4-methypyrazole
Human cytochrome P450 2E1 with 4-methypyrazole.
Human cytochrome P450 2E1 with indazole
Human cytochrome P450 2E1 with indazole.
Proline 4-hydroxylase from <i>Bacillus anthracis</i>
Proline 4-hydroxylase from Bacillus anthracis.
NADPH-Cytochrome P450 reductase FMN-containing domain with FMN in black sticks
NADPH-Cytochrome P450 reductase FMN-containing domain with FMN in black sticks
Cytochrome P450 2B4 movie between open and closed conformations
Cytochrome P450 2B4 movie morphing between open and closed conformations.